Human Umbilical Endothelial Cell Conditioned Media

INCI: HUMAN UMBILICAL ENDOTHELIAL CELL CONDITIONED MEDIA

CAS Number
Not assigned
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not explicitly prohibited under 21 CFR 700; however, FDA may classify as biologic under 21 CFR 1271 (HCT/Ps). MoCRA requires safety substantiation.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

TSE and viral contamination risk; donor variability; no CIR review; EU-prohibited; potential biologic reclassification in the US.

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Concern Level: High

Frequently Asked Questions

Is Human Umbilical Endothelial Cell Conditioned Media safe in cosmetics?

TSE and viral contamination risk; donor variability; no CIR review; EU-prohibited; potential biologic reclassification in the US. The EU classifies Human Umbilical Endothelial Cell Conditioned Media as "prohibited". Safety rating: POOR.

Is Human Umbilical Endothelial Cell Conditioned Media allowed in the EU?

Human Umbilical Endothelial Cell Conditioned Media EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Human Umbilical Endothelial Cell Conditioned Media do in cosmetics?

Human Umbilical Endothelial Cell Conditioned Media functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Human Umbilical Endothelial Cell Conditioned Media?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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