Hydrastis Canadensis Extract (Goldenseal)

INCI: HYDRASTIS CANADENSIS EXTRACT

CAS Number
84603-60-1
Function
Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR prohibition for cosmetic use; CITES Appendix II listed plant (trade documentation required)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Berberine and hydrastine present embryotoxic and prohibited concerns; CITES Appendix II listing requires trade documentation; CPSR must quantify berberine and hydrastine content and demonstrate adequate margin of safety.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Hydrastis Canadensis Extract (Goldenseal) safe in cosmetics?

Berberine and hydrastine present embryotoxic and prohibited concerns; CITES Appendix II listing requires trade documentation; CPSR must quantify berberine and hydrastine content and demonstrate adequate margin of safety. The EU classifies Hydrastis Canadensis Extract (Goldenseal) as "prohibited". Safety rating: POOR.

Is Hydrastis Canadensis Extract (Goldenseal) allowed in the EU?

Hydrastis Canadensis Extract (Goldenseal) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrastis Canadensis Extract (Goldenseal) do in cosmetics?

Hydrastis Canadensis Extract (Goldenseal) functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84603-60-1.

What is the Margin of Safety for Hydrastis Canadensis Extract (Goldenseal)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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