Hydrochlorofluorocarbon 142b (HCFC-142b)
INCI: HYDROCHLOROFLUOROCARBON 142B
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Hydrochlorofluorocarbon 142b (HCFC-142b). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >20000 ppm | 1991 | rat | inhalation | REACH |
| NOAEL | >10000 ppm | 1991 | rat | inhalation | REACH |
| NOAEL | >10000 ppm | 1991 | dog | inhalation | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Ozone-depleting substance with significant global warming potential, banned globally under the Montreal Protocol and prohibited in all cosmetic products in the EU, US, and signatory nations.
Frequently Asked Questions
Is Hydrochlorofluorocarbon 142b (HCFC-142b) safe in cosmetics?
Ozone-depleting substance with significant global warming potential, banned globally under the Montreal Protocol and prohibited in all cosmetic products in the EU, US, and signatory nations. The EU classifies Hydrochlorofluorocarbon 142b (HCFC-142b) as "prohibited". Safety rating: POOR. 3 toxicological study endpoint(s) are available in our database.
Is Hydrochlorofluorocarbon 142b (HCFC-142b) allowed in the EU?
Hydrochlorofluorocarbon 142b (HCFC-142b) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrochlorofluorocarbon 142b (HCFC-142b) do in cosmetics?
Hydrochlorofluorocarbon 142b (HCFC-142b) functions as: Propellant, aerosol propellant. It is classified as a cosmetic ingredient in our database. CAS number: 75-68-3.
What is the Margin of Safety for Hydrochlorofluorocarbon 142b (HCFC-142b)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydrochlorofluorocarbon 142b (HCFC-142b)?
The NOAEL (No Observed Adverse Effect Level) for Hydrochlorofluorocarbon 142b (HCFC-142b) is >20000 ppm based on a inhalation study via 1991 route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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