Poor Cosmetic Ingredient

Hydrolyzed Calf Ligaments/Liver/Skin

INCI: HYDROLYZED CALF LIGAMENTS/LIVER/SKIN

CAS Number
Not assigned (complex animal-derived hydrolysate)
Function
Skin conditioning (collagen/elastin hydrolysate source)
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted with conditions — FDA requires BSE-free sourcing documentation; no specific CFR prohibition, but subject to USDA/APHIS import rules for bovine-derived materials

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

BSE/TSE prion risk — liver is a higher-risk organ; requires veterinary health certificate, country-of-origin BSE status (OIE classification), age of animal (<12 months), and validated processing documentation. COSMOS/ECOCERT non-compliant (animal-derived). Increasingly replaced by plant or marine collagen

⚠️
Concern Level: High

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Hydrolyzed Calf Ligaments/Liver/Skin safe in cosmetics?

BSE/TSE prion risk — liver is a higher-risk organ; requires veterinary health certificate, country-of-origin BSE status (OIE classification), age of animal (<12 months), and validated processing documentation. COSMOS/ECOCERT non-compliant (animal-derived). Increasingly replaced by plant or marine collagen The EU classifies Hydrolyzed Calf Ligaments/Liver/Skin as "prohibited". Safety rating: POOR.

Is Hydrolyzed Calf Ligaments/Liver/Skin allowed in the EU?

Hydrolyzed Calf Ligaments/Liver/Skin EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Calf Ligaments/Liver/Skin do in cosmetics?

Hydrolyzed Calf Ligaments/Liver/Skin functions as: Skin conditioning (collagen/elastin hydrolysate source). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex animal-derived hydrolysate).

What is the Margin of Safety for Hydrolyzed Calf Ligaments/Liver/Skin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hydrolyzed Calf Ligaments/Liver/Skin compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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