Also known as: β-Cyclodextrin, 2-hydroxypropyl ethers, 5,10,15,25-tetrakis(hydroxymethyl)-40,44,47,49-tetrakis(2-hydroxypropoxy)-20,30,35-tris[(2-hydroxypropoxy)methyl]-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.2^{3,6}.2^{8,11}.2^{13,16}.2^{18,21}.2^{23,26}.2^{28,31}]nonatetracontane-36,37,38,39,41,42,43,45,46,48-decol, EC No.: 420-920-1, 2-Hydroxypropyl-.beta.-cyclodextrine ethers, C'Cavitron 82006 (+9 more)
INCI: HYDROXYPROPYL CYCLODEXTRIN
Hydroxypropyl Beta-Cyclodextrin — Deep Resear (CAS 128446-35-5) is a cosmetic cosmetic ingredient functioning as Insufficient Data. Reported NOAEL =1000 mg/kg bw/day in Rabbit (ECHA); EU Regulation 1223/2009 status: permitted, max 2%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 128446-35-5 →
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Margin of Safety, dermal absorption, and sensitization profile summaries for Hydroxypropyl Beta-Cyclodextrin — Deep Resear.
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1 study endpoint found for Hydroxypropyl Beta-Cyclodextrin — Deep Resear. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rabbit | developmental | ECHA |
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Preliminary editorial summary for Hydroxypropyl Beta-Cyclodextrin — Deep Resear — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to Hydroxypropyl Beta-Cyclodextrin — Deep Resear by CAS number or substance name.
Same-CAS public records found in pharmaceutical data.
Same-CAS rows from the pharmaceutical spoke database.
Hydroxypropyl Beta-Cyclodextrin — Deep Resear has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Hydroxypropyl Beta-Cyclodextrin — Deep Resear EU regulatory status: permitted. Maximum allowed concentration: 2%. This is based on EU Regulation 1223/2009 and its amendments.
Hydroxypropyl Beta-Cyclodextrin — Deep Resear functions as: Insufficient Data. It is classified as a cosmetic ingredient in our database. CAS number: 128446-35-5.
The NOAEL (No Observed Adverse Effect Level) for Hydroxypropyl Beta-Cyclodextrin — Deep Resear is =1000 mg/kg bw/day based on a developmental study via oral route in Rabbit. Source: ECHA.
Hydroxypropyl Beta-Cyclodextrin — Deep Resear also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
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