Excellent Cosmetic Ingredient GHS Classified

Isobutyl Acetate

CAS Number
110-19-0
Function
Flavouring and nutrient; Fragrance; No specific technical function; Solvent
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — FEMA GRAS (No. 2175); no CFR restriction for cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The vapour is mildly irritating to the eyes and respiratory tract. The substance may cause effects on the central nervous system. Exposure far above the OEL could cause lowering of consciousness.
Long-term Exposure Effects
The substance defats the skin, which may cause dryness or cracking.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its vapour.

Expert Verdict

Flammable liquid (H225); narcotic at high concentrations via inhalation (H336); ensure adequate ventilation in manufacturing; no dermal safety concern in finished product

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isobutyl Acetate safe in cosmetics?

Flammable liquid (H225); narcotic at high concentrations via inhalation (H336); ensure adequate ventilation in manufacturing; no dermal safety concern in finished product The EU classifies Isobutyl Acetate as "permitted". Safety rating: EXCELLENT.

Is Isobutyl Acetate allowed in the EU?

Isobutyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Acetate do in cosmetics?

Isobutyl Acetate functions as: Flavouring and nutrient; Fragrance; No specific technical function; Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 110-19-0.

What is the Margin of Safety for Isobutyl Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Isobutyl Acetate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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