Isocineole

INCI: ISOCINEOLE

CAS Number
470-67-7
Function
Fragrance / masking agent; monoterpene ether
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” FEMA GRAS; no specific FDA restriction in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Eye irritant (R36); flammable (R10); enhances percutaneous absorption of co-formulated actives; distinct from 1,8-cineole (eucalyptol) which has different safety profile

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Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Isocineole safe in cosmetics?

Eye irritant (R36); flammable (R10); enhances percutaneous absorption of co-formulated actives; distinct from 1,8-cineole (eucalyptol) which has different safety profile The EU classifies Isocineole as "permitted". Safety rating: MODERATE.

Is Isocineole allowed in the EU?

Isocineole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isocineole do in cosmetics?

Isocineole functions as: Fragrance / masking agent; monoterpene ether. It is classified as a cosmetic ingredient in our database. CAS number: 470-67-7.

What is the Margin of Safety for Isocineole?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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