Isodecylparaben

INCI: ISODECYLPARABEN

CAS Number
Not widely published (long-chain paraben; limited commercial use)
Function
Preservative
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically restricted under 21 CFR; however, MoCRA (2022) imposes safety substantiation requirements. No CIR review exists.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Isodecylparaben cannot be legally used as a preservative in the EU (not in Annex V), has no SCCS or CIR safety assessment, exhibits greater estrogenic potency than shorter-chain parabens, and lacks published toxicological data supporting its safety.

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Concern Level: High

Regulatory Flags

preservative

Frequently Asked Questions

Is Isodecylparaben safe in cosmetics?

Isodecylparaben cannot be legally used as a preservative in the EU (not in Annex V), has no SCCS or CIR safety assessment, exhibits greater estrogenic potency than shorter-chain parabens, and lacks published toxicological data supporting its safety. The EU classifies Isodecylparaben as "prohibited". Safety rating: POOR.

Is Isodecylparaben allowed in the EU?

Isodecylparaben EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Isodecylparaben do in cosmetics?

Isodecylparaben functions as: Preservative. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (long-chain paraben; limited commercial use).

What is the Margin of Safety for Isodecylparaben?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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