Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Isononyl Isononanoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | ca.600 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | ca.600 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 300 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Ultra-light dry-touch branched ester emollient improving spreadability and comfort in both lip gloss and matte liquid lipstick formulations. CIR confirms safety at cosmetic concentrations with no regulatory restrictions globally.
Regulatory Flags
Frequently Asked Questions
Is Isononyl Isononanoate safe in cosmetics?
Ultra-light dry-touch branched ester emollient improving spreadability and comfort in both lip gloss and matte liquid lipstick formulations. CIR confirms safety at cosmetic concentrations with no regulatory restrictions globally. The EU classifies Isononyl Isononanoate as "permitted". Safety rating: EXCELLENT. 4 toxicological study endpoint(s) are available in our database.
Is Isononyl Isononanoate allowed in the EU?
Isononyl Isononanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isononyl Isononanoate do in cosmetics?
Isononyl Isononanoate functions as: emollient, skin-conditioning. It is classified as a Emollient in our database. CAS number: 42131-25-9.
What is the Margin of Safety for Isononyl Isononanoate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Isononyl Isononanoate?
The NOAEL (No Observed Adverse Effect Level) for Isononyl Isononanoate is ca.600 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
Check Isononyl Isononanoate compliance across multiple jurisdictions:
Related Ingredients
Is Isononyl Isononanoate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Isononyl Isononanoate in your formulation.