Is ISOPHTHALIC ACID safe in cosmetics?
ISOPHTHALIC ACID has a safety rating of "GOOD" in our database. EU status: permitted.
ISOPHTHALIC ACID
Also known as: 3-Carboxybenzoic acid, Isoterephthalic acid, 1,3-Benzenedicarboxylic acid, 4-09-00-03292, BRN 1909332 (+4 more)
ISOPHTHALIC ACID (CAS 121-91-5) is a cosmetic cosmetic ingredient functioning as Not Reported. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 121-91-5 →
Auto-generated CPSR Part A draft with source citations
Function
Not Reported
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
benzene-1,3-dicarboxylic acid
InChIKey
QQVIHTHCMHWDBS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Hazard Statements
No hazard classification according to GHS criteria
Short-term Exposure Effects
May cause mechanical irritation to the eyes.
Routes of Exposure
The substance can be absorbed into the body by ingestion.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100,000 - 1,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
ICSC Safety Card
0500
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Skin Eye Respiratory Irritation
An eye irritant.
Source: Hazardous Substances Data Bank (HSDB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
No specific technical function
Solvent
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for ISOPHTHALIC ACID.
Regulatory Flags
cosing-sourced
eu-permitted
needs-enrichment
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to ISOPHTHALIC ACID by CAS number or substance name.
Studies
3
Lowest NOAEL
142 mg/kg bw/day
Highest NOAEL
142 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
3-Carboxybenzoic acid
Isoterephthalic acid
1,3-Benzenedicarboxylic acid
4-09-00-03292
BRN 1909332
EINECS 204-506-4
Kyselina isoftalova
UNII-X35216H9FJ
meta-benzenedicarboxylic acid
Chemical Function
Solvent
No specific technical function
Regulatory Lists
drinking_water; Europe; manufacturing; plastic_additive
inert_ingredient; non_food_use; Pesticides
CEDI
Indirect additives food contact (10/2018)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ISOPHTHALIC ACID
ChEMBL ID
CHEMBL1871181
Frequently Asked Questions
Is ISOPHTHALIC ACID allowed in the EU?
ISOPHTHALIC ACID EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does ISOPHTHALIC ACID do in cosmetics?
ISOPHTHALIC ACID functions as: Not Reported. It is classified as a cosmetic ingredient in our database. CAS number: 121-91-5.
Is ISOPHTHALIC ACID used outside cosmetics?
ISOPHTHALIC ACID also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check ISOPHTHALIC ACID compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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