Moderate Cosmetic Ingredient GHS Classified

Isopropylideneglycerol

INCI: ISOPROPYLIDENEGLYCEROL

CAS Number
100-79-8
Function
Solvent, humectant, skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Permitted, not listed as prohibited or restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol.

Expert Verdict

H361d (GHS) suspected of damaging the unborn child (Repr. Cat. 2 per CLP). CMR Cat. 2 triggers Article 15 review under EU 1223/2009. Requires SCCS evaluation if challenged. Eye irritant (H319)

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Concern Level: Moderate

Regulatory Flags

epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is Isopropylideneglycerol safe in cosmetics?

H361d (GHS) suspected of damaging the unborn child (Repr. Cat. 2 per CLP). CMR Cat. 2 triggers Article 15 review under EU 1223/2009. Requires SCCS evaluation if challenged. Eye irritant (H319) The EU classifies Isopropylideneglycerol as "restricted". Safety rating: MODERATE.

Is Isopropylideneglycerol allowed in the EU?

Isopropylideneglycerol EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropylideneglycerol do in cosmetics?

Isopropylideneglycerol functions as: Solvent, humectant, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 100-79-8.

What is the Margin of Safety for Isopropylideneglycerol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Isopropylideneglycerol compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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