Is Isostearyl Palmitate safe in cosmetics?
Isostearyl Palmitate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Isostearyl Palmitate
Also known as: EINECS 276-719-0, UNII-9EHU0R7ER1
INCI: ISOSTEARYL PALMITATE
Isostearyl Palmitate (CAS 72576-80-8) is a cosmetic cosmetic ingredient functioning as Emollient, Binder, Skin Conditioning. NOAEL 300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 72576-80-8 →
Auto-generated CPSR Part A draft with source citations
Function
Emollient, Binder, Skin Conditioning
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
16-methylheptadecyl hexadecanoate
InChIKey
SAMYFBLRCRWESN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR-reviewed as safe within the isostearyl esters group; FDA UNII: 9EHU0R7ER1
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Isostearyl Palmitate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Isostearyl Palmitate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Binder
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Isostearyl Palmitate.
Regulatory Flags
potential-allergen
Known Synonyms
EINECS 276-719-0
UNII-9EHU0R7ER1
Chemical Function
Softener and conditioner
Binder
Regulatory Lists
Europe; plastic_additive
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Isostearyl Palmitate allowed in the EU?
Isostearyl Palmitate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isostearyl Palmitate do in cosmetics?
Isostearyl Palmitate functions as: Emollient, Binder, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 72576-80-8.
Is Isostearyl Palmitate used outside cosmetics?
Isostearyl Palmitate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Isostearyl Palmitate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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