Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Isostearyl Palmitate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 300 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Non-comedogenic, non-irritating emollient suitable for hypoallergenic formulations.
Regulatory Flags
Frequently Asked Questions
Is Isostearyl Palmitate safe in cosmetics?
Non-comedogenic, non-irritating emollient suitable for hypoallergenic formulations. The EU classifies Isostearyl Palmitate as "permitted". Safety rating: EXCELLENT. 10 toxicological study endpoint(s) are available in our database.
Is Isostearyl Palmitate allowed in the EU?
Isostearyl Palmitate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Isostearyl Palmitate do in cosmetics?
Isostearyl Palmitate functions as: Emollient, Binder, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 72576-80-8.
What is the Margin of Safety for Isostearyl Palmitate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Isostearyl Palmitate?
The NOAEL (No Observed Adverse Effect Level) for Isostearyl Palmitate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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