Jacobaea Vulgaris Extract ⚠️

INCI: JACOBAEA VULGARIS EXTRACT

CAS Number
84929-37-3 (as Senecio jacobaea extract)
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status prohibited
US Notes FDA considers pyrrolizidine alkaloid-containing botanicals adulterated under FD&C Act when presenting a health hazard

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: Contains hepatotoxic, genotoxic, and carcinogenic pyrrolizidine alkaloids; EMA explicitly identifies Senecio jacobaea as a major PA source; not acceptable in any cosmetic formulation; reject immediately if encountered in supply chain.

⚠️
Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Jacobaea Vulgaris Extract ⚠️ safe in cosmetics?

CRITICAL: Contains hepatotoxic, genotoxic, and carcinogenic pyrrolizidine alkaloids; EMA explicitly identifies Senecio jacobaea as a major PA source; not acceptable in any cosmetic formulation; reject immediately if encountered in supply chain. The EU classifies Jacobaea Vulgaris Extract ⚠️ as "prohibited". Safety rating: POOR.

Is Jacobaea Vulgaris Extract ⚠️ allowed in the EU?

Jacobaea Vulgaris Extract ⚠️ EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Jacobaea Vulgaris Extract ⚠️ do in cosmetics?

Jacobaea Vulgaris Extract ⚠️ functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84929-37-3 (as Senecio jacobaea extract).

What is the Margin of Safety for Jacobaea Vulgaris Extract ⚠️?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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