Levistolide A

INCI: LEVISTOLIDE A

CAS Number
88182-33-6 (Sigma-Aldrich) / 89708-23-6 (alternate registry)
Function
Skin conditioning (research-stage; isolated from Ligusticum chuanxiong)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not established โ€” no CFR listing; no CIR review; no VCRP use data

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Research compound with high biological potency used in cancer research contexts. No published toxicological data (NOAEL, repeat-dose studies, genotoxicity screening) for cosmetic safety endpoints. Molecular weight 380.48 falls within dermal-absorbable range. Not suitable for cosmetic use without comprehensive toxicological dossier.

โš ๏ธ
Concern Level: High

Frequently Asked Questions

Is Levistolide A safe in cosmetics?

Research compound with high biological potency used in cancer research contexts. No published toxicological data (NOAEL, repeat-dose studies, genotoxicity screening) for cosmetic safety endpoints. Molecular weight 380.48 falls within dermal-absorbable range. Not suitable for cosmetic use without comprehensive toxicological dossier. The EU classifies Levistolide A as "permitted". Safety rating: POOR.

Is Levistolide A allowed in the EU?

Levistolide A EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Levistolide A do in cosmetics?

Levistolide A functions as: Skin conditioning (research-stage; isolated from Ligusticum chuanxiong). It is classified as a cosmetic ingredient in our database. CAS number: 88182-33-6 (Sigma-Aldrich) / 89708-23-6 (alternate registry).

What is the Margin of Safety for Levistolide A?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Levistolide A in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Levistolide A in your formulation.