Regulatory Status
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Safety Data
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Expert Verdict
Sesquiterpene lactone class carries inherent sensitization risk with no existing cosmetic-grade safety dossier, CIR review, or SCCS assessment; would require comprehensive de novo toxicological evaluation including acute toxicity, repeat-dose studies, genotoxicity, sensitization, and phototoxicity testing before any cosmetic application.
Regulatory Flags
Frequently Asked Questions
Is Linderanolide B / Subamolide A safe in cosmetics?
Sesquiterpene lactone class carries inherent sensitization risk with no existing cosmetic-grade safety dossier, CIR review, or SCCS assessment; would require comprehensive de novo toxicological evaluation including acute toxicity, repeat-dose studies, genotoxicity, sensitization, and phototoxicity testing before any cosmetic application. The EU classifies Linderanolide B / Subamolide A as "permitted". Safety rating: POOR.
Is Linderanolide B / Subamolide A allowed in the EU?
Linderanolide B / Subamolide A EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Linderanolide B / Subamolide A do in cosmetics?
Linderanolide B / Subamolide A functions as: Skin conditioning, bioactive compound with reported anti-inflammatory activity in preclinical studies. It is classified as a cosmetic ingredient in our database. CAS number: Not commonly assigned for cosmetic use; research-only identifiers in phytochemistry literature.
What is the Margin of Safety for Linderanolide B / Subamolide A?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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