Lysine HCl

INCI: LYSINE HCL

CAS Number
657-27-2 [^1_11][^1_12]
Function
Skin conditioning, hair conditioning, antistatic
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” referenced under 21 CFR 310.545; also GRAS for food use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Best-characterized ingredient with extensive safety history; essential amino acid salt with no significant safety concerns.

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Concern Level: None

Frequently Asked Questions

Is Lysine HCl safe in cosmetics?

Best-characterized ingredient with extensive safety history; essential amino acid salt with no significant safety concerns. The EU classifies Lysine HCl as "permitted". Safety rating: EXCELLENT.

Is Lysine HCl allowed in the EU?

Lysine HCl EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Lysine HCl do in cosmetics?

Lysine HCl functions as: Skin conditioning, hair conditioning, antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 657-27-2 [^1_11][^1_12].

What is the Margin of Safety for Lysine HCl?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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