Is Magnesium Carbonate safe in cosmetics?
Magnesium Carbonate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Magnesium Carbonate
Also known as: Carbonic acid, magnesium salt (1:1), Apolda, C.I. 77713, CSC Book Saver, CSC Book Saver Spray (+14 more)
INCI: MAGNESIUM CARBONATE
Magnesium Carbonate (CAS 546-93-0) is a cosmetic cosmetic ingredient functioning as Absorbent, Bulking Agent, Mattifying, Opacifying, pH Adjuster, Anti-Caking,. Reported NOAEL =290 mg/kg body weight/d (CIR_vision_codex); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 546-93-0 →
Auto-generated CPSR Part A draft with source citations
Function
Absorbent, Bulking Agent, Mattifying, Opacifying, pH Adjuster, Anti-Caking, Abrasive
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
magnesium carbonate
InChIKey
ZLNQQNXFFQJAID-UHFFFAOYSA-L
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS as direct food additive. Approved as inactive ingredient in oral drug products. 317 VCRP formulations as of 2016.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Magnesium Carbonate.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Magnesium Carbonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =290 mg/kg body weight/d | - | - | NOAEL study | CIR_vision_codex |
| NOAEL | =290 mg/kg body weight/d | - | - | NOAEL study | CIR_vision_codex |
| NOAEL | =290 mg/kg body weight/d | - | - | NOAEL study | CIR_vision_codex |
| NOAEL | =290 mg/kg body weight/d | - | - | NOAEL study | CIR_vision_codex |
| NOAEL | =414 mg/kg body weight/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =414 mg/kg body weight/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =414 mg/kg body weight/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =414 mg/kg body weight/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =1000 mg/kg body weight/d | oral | rat | developmental toxicity | CIR_vision_codex |
| NOAEL | =1000 mg/kg body weight/d | oral | rat | developmental toxicity | CIR_vision_codex |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Hazard Statements
No hazard classification according to GHS criteria
Long-term Exposure Effects
Lungs may be affected by repeated or prolongated exposure to dust particles.
Routes of Exposure
The substance can be absorbed into the body by inhalation.
EPA ToxValDB — Toxicity Values
1 toxicity value from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).
| Endpoint | Value | Species | Route | Duration | Source |
|---|---|---|---|---|---|
| LD50 | >2000 mg/kg | Rat | oral | - | ECHA IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
GROUP; SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
6 property records from structured ingredient metadata.
colorant_formulator
{"ci_number": "77713", "ci_name": "Filler", "color_category": "white", "color_hex_code": "#FFFEFC", "natural_or_synthetic": "synthetic", "organic_or_inorganic": "inorganic", "lake_or_dye": "pigment", "fda_approved_use": "lip/eye/general", "eu_approved_cosmetic": "yes", "japan_approved": "yes", "china_approved": "yes", "coverage_opacity": "opaque", "tinting_strength": "medium", "lightfastness_ratin…
deodorant
{"cas_number": "546-93-0", "ingredient_class": "sweat_absorber", "mechanism_of_action": "odor_absorption", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "8-12", "odor_reduction_pct": "30-50", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", "a…
ecotoxicity
{"biodegradable": "no", "biodegradation_days": "non-biodegradable", "bioaccumulative": "no", "aquatic_toxicity_level": "low", "coral_reef_safe": "yes", "marine_toxicity": "very low toxicity", "freshwater_toxicity": "minimal impact", "endocrine_disruptor": "no", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_environmental": "…
mineral_clay
{"cas_number": "546-93-0", "ingredient_class": "magnesium_compound", "chemical_formula": "MgCO3", "mineral_origin": "natural", "particle_size_range_um": "1-30", "surface_area_m2_per_g": "5-20", "crystal_structure": "trigonal", "color_appearance": "white", "opacity": "opaque", "refractive_index": "1.55", "oil_absorption_g_per_100g": "60-120", "water_absorption_capacity": "100-200%", "surface_charge…
sensory
{"silky": "powdery", "smooth, glides easily": "light, absorbing", "dry-touch, non-greasy": "dry, matte", "instant": "fast", "low": "low", "w/o": "o/w", "very-high": "moderate", "no": "no", "yes": "no", "light-diffusing": "matte", "1.40": "3.00", "transparent": "opaque", "colorless": "white", "excellent": "fair", "light": "light", "synthetic": "mineral"}
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "acceptable", "sensitive_skin": "acceptable", "combination_skin": "acceptable", "normal_skin": "acceptable", "acne_prone": "acceptable", "rosacea": "acceptable", "eczema": "acceptable", "hyperpigmentation": "acceptable", "aging_mature": "acceptable", "dehydrated": "acceptable", "skin_benefit_primary": "oil-absorbing", "skin_benefit_secondary": "pH-adjusting"…
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
ICSC Safety Card
0969
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (2)
JECFA Evaluation
MAGNESIUM CARBONATE | 1965 | NOT LIMITED | NMRS 40/TRS 339-JECFA 9/16 | FAS 67.29/NMRS 40A,B,C-JECFA 9/159
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Absorbent
Binder
Dye
Filler
Flame retardant
Flow promoter
Heat stabilizer
Opacifer
Processing aids not otherwise specified
Stabilizing agent
Regulatory List Membership (3)
EU Regulated in Personal Care
EPA Safer Chemical Ingredients List (SCIL)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Magnesium Carbonate.
Regulatory Flags
epa_safer_alternative
eu_cosing_listed
jecfa_safe
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Magnesium Carbonate by CAS number or substance name.
Studies
29
Lowest NOAEL
290
Highest NOAEL
4128
Units vary across source rows: mg/kg body weight/d, mg/kg body weight, mg/kg bw/day
CIR_vision_codex
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Carbonic acid, magnesium salt (1:1)
Apolda
C.I. 77713
CSC Book Saver
CSC Book Saver Spray
Carbonate magnesium
DCI Light Magnesium Carbonate
Destab
Frimiz MZ 1
GP 20 (carbonate)
Gold Star (carbonate)
Kimboshi
MA 70 (carbonate)
MSL-AM
Upsalite
TT (carbonate)
Magnesite 33
Magnesite MSS
Magnesium Carbonate Gold Star
Chemical Function
Absorbent
Dye
Opacifer
Filler
Binder
pH regulating agent
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
inert_ingredient; non_food_use; Pesticides
drinking_water; Europe; manufacturing; plastic_additive
active_ingredient; animal_products; Europe; pharmaceutical; residue
Europe; supplements
Europe; food_additive; supplements
Europe; plastic_additive
Europe; Personal care
SCIL (9/2019)
Canada; pharmaceutical
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MAGNESIUM CARBONATE
ChEMBL ID
CHEMBL1200736
Max Phase
4
Adverse Event Associations
58
Frequently Asked Questions
Is Magnesium Carbonate allowed in the EU?
Magnesium Carbonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Magnesium Carbonate do in cosmetics?
Magnesium Carbonate functions as: Absorbent, Bulking Agent, Mattifying, Opacifying, pH Adjuster, Anti-Caking, Abrasive. It is classified as a cosmetic ingredient in our database. CAS number: 546-93-0.
What is the NOAEL for Magnesium Carbonate?
The NOAEL (No Observed Adverse Effect Level) for Magnesium Carbonate is =290 mg/kg body weight/d based on a NOAEL study study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.
Is Magnesium Carbonate used outside cosmetics?
Magnesium Carbonate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Magnesium Carbonate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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