Is Zinc Citrate safe in cosmetics?
Zinc Citrate has a safety rating of "EXCELLENT" in our database. EU status: restricted. US status: permitted.
EXCELLENT
Cosmetic Ingredient
Zinc Citrate
INCI: ZINC CITRATE
Zinc Citrate (CAS 546-46-3) is a cosmetic cosmetic ingredient functioning as Oral care agent, deodorant agent, skin conditioning agent. EU Regulation 1223/2009 status: restricted, max 1%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
Function
Oral care agent, deodorant agent, skin conditioning agent
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
trizinc bis(2-hydroxypropane-1,2,3-tricarboxylate)
InChIKey
WGIWBXUNRXCYRA-UHFFFAOYSA-H
Regulatory Status
EU EU Status
restricted
EU Max Conc.
1%
US US Status
permitted
US Notes
CIR previously reviewed (2014) and concluded safe; reaffirmed in 2018 group assessment
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Zinc Citrate.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Pharmaceutical
Editorial summary
Preliminary editorial summary for Zinc Citrate — not a computed safety verdict. See the sourced toxicological data above.
Chemical Function
Pharmaceutical
Biocide
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Europe; supplements
Europe; food_additive; supplements
Canada; pharmaceutical
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA count match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Adverse Event Associations
90
Frequently Asked Questions
Is Zinc Citrate allowed in the EU?
Zinc Citrate EU regulatory status: restricted. Maximum allowed concentration: 1%. This is based on EU Regulation 1223/2009 and its amendments.
What does Zinc Citrate do in cosmetics?
Zinc Citrate functions as: Oral care agent, deodorant agent, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 546-46-3.
Is Zinc Citrate used outside cosmetics?
Zinc Citrate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Zinc Citrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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