Also known as: D-Glucitol, 4-O-alpha-D-glucopyranosyl-, Amalty, Lesys, Lycasin HBC, Mabit (+15 more)
INCI: MALTITOL
Maltitol (CAS 585-88-6) is a cosmetic cosmetic ingredient functioning as Humectant, masking agent, moisturising. Reported NOAEL =7600 mg/kg bw/day in Rat (EFSA); EU Regulation 1223/2009 status: permitted; 2 safety opinions reviewed (CIR Safety Assessment). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 585-88-6 →
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Margin of Safety, dermal absorption, and sensitization profile summaries for Maltitol.
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4 study endpoints found for Maltitol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =7600 mg/kg bw/day | oral: feed | Rat | subchronic | EFSA |
| NOAEL | =7600 mg/kg bw/day | oral: feed | Rat | subchronic | EFSA |
| NOAEL | =15400 mg/kg bw/day | oral: feed | Rat | subchronic | EFSA |
| NOAEL | =15400 mg/kg bw/day | oral: feed | Rat | subchronic | EFSA |
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
ty test data were available for Maltitol Laurate, the Panel concluded that the safety Maltitol Laurate may be inferred based on the available data for Maltitol and for Lauric Acid, the two hydrolysis products of Maltitol Laurate (a previous safety assessment of Lauric Acid completed
ty test data were available for Maltitol Laurate, the Panel concluded that the safety Maltitol Laurate may be inferred based on the available data for Maltitol and for Lauric Acid, the two hydrolysis products of Maltitol Laurate (a previous safety assessment of Lauric Acid completed
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
8 property records from structured ingredient metadata.
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Expert safety assessment and concern-level summary for Maltitol.
Public NOAEL study rows linked to Maltitol by CAS number or substance name.
Same-CAS public records found in food safety data.
Same-CAS food additive or FDA GRAS records from the core public database.
Maltitol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 4 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by CIR Safety Assessment.
Maltitol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Maltitol functions as: Humectant, masking agent, moisturising. It is classified as a cosmetic ingredient in our database. CAS number: 585-88-6.
The NOAEL (No Observed Adverse Effect Level) for Maltitol is =7600 mg/kg bw/day based on a subchronic study via oral: feed route in Rat. A total of 4 study endpoints are available. Source: EFSA.
Maltitol also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
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