N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Toxicological Studies
2 study endpoints found for N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 5 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| LOAEL | 20 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
Expert Verdict
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE is listed in the EU CosIng database with functions: Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: III/198.
Regulatory Flags
Frequently Asked Questions
Is N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE safe in cosmetics?
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE is listed in the EU CosIng database with functions: Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: III/198. The EU classifies N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE as "Restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.
Is N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE allowed in the EU?
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE EU regulatory status: Restricted. Maximum allowed concentration: III/198. This is based on EU Regulation 1223/2009 and its amendments.
What does N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE do in cosmetics?
N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE functions as: Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 54381-16-7.
What is the NOAEL for N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE?
The NOAEL (No Observed Adverse Effect Level) for N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE is 5 mg/kg bw/day based on a Developmental study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
Check N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE compliance across multiple jurisdictions:
Related Ingredients
Is N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for N,N-BIS(2-HYDROXYETHYL)-P-PHENYLENEDIAMINE SULFATE in your formulation.