Good Active Ingredient GHS Classified SCCS/CIR Reviewed

NITROCELLULOSE

CAS Number
9004-70-0
Function
Film-forming agent; nail lacquer primary film former; adhesive
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 22%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: safe in present practices of use; max 22% in nail polish/enamels; cosmetic grade nitrogen content 10.7โ€“12.2%; DOT/OSHA flammability classification applies to manufacturing and storage; not individually FDA-approved but acceptable under FD&C Act

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
flam;flame
Hazard Statements
Flammable solid
Short-term Exposure Effects
See Notes.
Long-term Exposure Effects
See Notes.
Routes of Exposure
See Notes.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe

Panel concluded that nitrocellulose and collodion are safe in cosmetics in the present practices of use and concentration described in this safety assessment. Authorsโ€™ Note M. Fiume contributed to the conception and design, acquisition, anal- ysis, and interpretation and drafted the manuscript;

Expert Verdict

Safe at โ‰ค22% in nail lacquers when cosmetic-grade material (controlled nitrogen content, solvent-wetted for flammability control) is used. Manufacturing and storage flammability controls are mandatory.

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Concern Level: Low

Regulatory Flags

flammability-manufacturing-hazard nail-product-use solvent-vehicle-penetration

Frequently Asked Questions

Is NITROCELLULOSE safe in cosmetics?

Safe at โ‰ค22% in nail lacquers when cosmetic-grade material (controlled nitrogen content, solvent-wetted for flammability control) is used. Manufacturing and storage flammability controls are mandatory. The EU classifies NITROCELLULOSE as "permitted". Safety rating: GOOD. This ingredient has been reviewed by cir.

Is NITROCELLULOSE allowed in the EU?

NITROCELLULOSE EU regulatory status: permitted. Maximum allowed concentration: 22%. This is based on EU Regulation 1223/2009 and its amendments.

What does NITROCELLULOSE do in cosmetics?

NITROCELLULOSE functions as: Film-forming agent; nail lacquer primary film former; adhesive. It is classified as a Active Ingredient in our database. CAS number: 9004-70-0.

What is the Margin of Safety for NITROCELLULOSE?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Is NITROCELLULOSE classified as hazardous under GHS?

NITROCELLULOSE carries a GHS signal word of "DANGER". Hazard statements: Flammable solid. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance โ€” at cosmetic use concentrations, hazard thresholds may not be met.

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