O-Allyloxyanisole

INCI: O-ALLYLOXYANISOLE

CAS Number
1516-12-3 (2-(allyloxy)anisole / 1-methoxy-2-(prop-2-en-1-yloxy)benzene)
Function
Fragrance
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not listed as prohibited under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Structural analog estragole is classified GHS Mutagen Cat. 2, Carcinogen Cat. 2; SCCS Opinion on estragole flagged genotoxic potential via 1-hydroxylation pathway; this compound shares the allyl ether pharmacophore; QSAR/read-across strongly recommended; compound-specific genotoxicity data required before use.

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Concern Level: High

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is O-Allyloxyanisole safe in cosmetics?

Structural analog estragole is classified GHS Mutagen Cat. 2, Carcinogen Cat. 2; SCCS Opinion on estragole flagged genotoxic potential via 1-hydroxylation pathway; this compound shares the allyl ether pharmacophore; QSAR/read-across strongly recommended; compound-specific genotoxicity data required before use. The EU classifies O-Allyloxyanisole as "permitted". Safety rating: POOR.

Is O-Allyloxyanisole allowed in the EU?

O-Allyloxyanisole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does O-Allyloxyanisole do in cosmetics?

O-Allyloxyanisole functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 1516-12-3 (2-(allyloxy)anisole / 1-methoxy-2-(prop-2-en-1-yloxy)benzene).

What is the Margin of Safety for O-Allyloxyanisole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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