Good Active Ingredient

Palmitoyl Dipeptide-6 Diaminohydroxybutyrate

INCI: PALMITOYL DIPEPTIDE-6 DIAMINOHYDROXYBUTYRATE

Function
Anti-aging peptide; skin conditioning
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not restricted by FDA. Used in OTC anti-aging formulations targeting the dermal-epidermal junction (DEJ). Part of SYN-TACKS peptide complex by DSM-Firmenich. No safety concerns at typical 0.5-2% use.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CAS 794590-34-4. EU: Permitted (CosIng INCI inventory); not listed in Annexes II-VI of EC 1223/2009. US: Not prohibited by FDA; no CIR individual monograph; covered under palmitoyl oligopeptides class review. Trade name: SYN-TACKS (DSM-Firmenich).

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Concern Level: Low

Regulatory Flags

no-cir-individual-review limited-absorption-data inci-name-updated-2020 anti-aging-peptide

Frequently Asked Questions

Is Palmitoyl Dipeptide-6 Diaminohydroxybutyrate safe in cosmetics?

CAS 794590-34-4. EU: Permitted (CosIng INCI inventory); not listed in Annexes II-VI of EC 1223/2009. US: Not prohibited by FDA; no CIR individual monograph; covered under palmitoyl oligopeptides class review. Trade name: SYN-TACKS (DSM-Firmenich). The EU classifies Palmitoyl Dipeptide-6 Diaminohydroxybutyrate as "permitted". Safety rating: GOOD.

Is Palmitoyl Dipeptide-6 Diaminohydroxybutyrate allowed in the EU?

Palmitoyl Dipeptide-6 Diaminohydroxybutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Palmitoyl Dipeptide-6 Diaminohydroxybutyrate do in cosmetics?

Palmitoyl Dipeptide-6 Diaminohydroxybutyrate functions as: Anti-aging peptide; skin conditioning. It is classified as a Active Ingredient in our database.

What is the Margin of Safety for Palmitoyl Dipeptide-6 Diaminohydroxybutyrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Palmitoyl Dipeptide-6 Diaminohydroxybutyrate compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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