Good Active Ingredient SCCS/CIR Reviewed

Panax Ginseng Root Extract

Also known as: Panax schinseng, Korean red ginseng, UNII-CUQ3A77YXI

INCI: PANAX GINSENG ROOT EXTRACT

Panax Ginseng Root Extract (CAS 50647-08-0) is a cosmetic active ingredient functioning as dermal papilla proliferation stimulant; hair-growth active; adaptogen;. EU Regulation 1223/2009 status: permitted; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.

View industrial chemical safety profile for CAS 50647-08-0 →

Auto-generated CPSR Part A draft with source citations
Function
dermal papilla proliferation stimulant; hair-growth active; adaptogen; anti-inflammatory; antioxidant
Safety Rating
GOOD

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted cosmetic active. No OTC drug monograph applies. Used as cosmetic active and oral adaptogen supplement — different regulatory pathways.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Panax Ginseng Root Extract.

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe

ts and other ingredients, such as peppermint oil. The Panel concluded that these Panax spp root-derived ingredients are safe in the practices of use and concentration as given in this safety assessment. Keywords Panax spp, ginseng, safety, cosmetics Introduction Panax ginseng C. A. Meyer of the Araliaceae family is also ca

Additional Ingredient Properties

4 property records from structured ingredient metadata.

acne
{"cas_number": "84650-12-4", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "5-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restrictio…
anti_aging
{"anti_aging_claim": "anti-wrinkle, firming, antioxidant-protection", "mechanism_of_action": "Ginsenosides, saponins", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "Mild", "wrinkle_reduction_pct": "10-18", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytotherapy Researc…
anti_pollution
{"cas_number": "90045-38-8", "ingredient_class": "Nrf2_activator", "primary_mechanism": "enzyme_induction", "pollution_types_targeted": "PM2_5/UV_A/ozone", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no",…
self_tanning
{"cas_number": "90045-38-8", "ingredient_class": "tan_accelerator", "tanning_mechanism": "melanin_stimulation", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "A…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Humectant Softener and conditioner

Expert Verdict

Expert safety assessment and concern-level summary for Panax Ginseng Root Extract.

Regulatory Flags

hair-growth-active dermal-papilla-stimulant adaptogen traditional-medicine limited-human-rct

Known Synonyms

Panax schinseng Korean red ginseng UNII-CUQ3A77YXI

Chemical Function

Softener and conditioner Humectant

Regulatory Lists

active_ingredient; animal_products; Europe; pharmaceutical; residue Canada; pharmaceutical Canada; pharmaceutical Canada; pharmaceutical

Cross-Vertical Safety Context

Same-CAS public records found in food safety data.

SOURCE EFSA / FDA GRAS food_additives

Food Safety Data

Same-CAS food additive or FDA GRAS records from the core public database.

Food Name
Ginseng extract
Food Category
preservative
View full food safety profile →

Frequently Asked Questions

Is Panax Ginseng Root Extract safe in cosmetics?

Panax Ginseng Root Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. This ingredient has been reviewed by cir.

Is Panax Ginseng Root Extract allowed in the EU?

Panax Ginseng Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Panax Ginseng Root Extract do in cosmetics?

Panax Ginseng Root Extract functions as: dermal papilla proliferation stimulant; hair-growth active; adaptogen; anti-inflammatory; antioxidant. It is classified as a Active Ingredient in our database. CAS number: 50647-08-0.

Is Panax Ginseng Root Extract used outside cosmetics?

Panax Ginseng Root Extract also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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