Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate

INCI: PICHIA R-SH-POLYPEPTIDE-1 FERMENT EXTRACT FILTRATE

CAS Number
Not assigned (CosIng Ref No. 97545)
Function
Skin conditioning, skin protecting
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically listed by FDA; recombinant peptides in cosmetics are not pre-market approved but must meet general safety requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Recombinant/GMO-derived polypeptide with r- prefix denoting recombinant origin and sh- denoting synthetic human sequence, expressed in genetically modified Pichia pastoris. EU Responsible Person must verify: residual recombinant DNA presence, GMO status of production organism, peptide identity and purity, and full bioactivity characterization. Supplier dossier essential for CPSR.

โš ๏ธ
Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate safe in cosmetics?

Recombinant/GMO-derived polypeptide with r- prefix denoting recombinant origin and sh- denoting synthetic human sequence, expressed in genetically modified Pichia pastoris. EU Responsible Person must verify: residual recombinant DNA presence, GMO status of production organism, peptide identity and purity, and full bioactivity characterization. Supplier dossier essential for CPSR. The EU classifies Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate as "permitted". Safety rating: POOR.

Is Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate allowed in the EU?

Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate do in cosmetics?

Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate functions as: Skin conditioning, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (CosIng Ref No. 97545).

What is the Margin of Safety for Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Pichia r-sh-Polypeptide-1 Ferment Extract Filtrate in your formulation.