Is Pigment Red 112 safe in cosmetics?
Pigment Red 112 has a safety rating of "POOR" in our database. EU status: prohibited. US status: prohibited.
Poor
Cosmetic Ingredient
Pigment Red 112
Also known as: 2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-[2-(2,4,5-trichlorophenyl)diazenyl]-, 3-Hydroxy-N-(o-tolyl)-4-((2,4,5-trichlorophenyl)azo)naphthalene-2-carboxamide, 2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-((2,4,5-trichlorophenyl)azo)-, EINECS 229-440-3, UNII-6S30UYY7FD
INCI: CI 12370
Pigment Red 112 (CAS 6535-46-2) is a cosmetic cosmetic ingredient functioning as Colorant. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 6535-46-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Pigment Red 112 is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H411, H413).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Chemistry & Identifiers
IUPAC Name
3-hydroxy-N-(2-methylphenyl)-4-[(2,4,5-trichlorophenyl)diazenyl]naphthalene-2-carboxamide
InChIKey
JQNJCQYNSLCFAC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
prohibited
US Notes
Not FDA-approved for cosmetic use; absent from 21 CFR Parts 73/74
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Pigment Red 112.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1346
(EC) 2013/344
Annex IV — Permitted Colorants
Product type: Red
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1346
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
India: Permitted Colorant
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Pigment
Regulatory List Membership (3)
EU Banned in Cosmetics
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Pigment Red 112.
Regulatory Flags
colorant
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-[2-(2,4,5-trichlorophenyl)diazenyl]-
3-Hydroxy-N-(o-tolyl)-4-((2,4,5-trichlorophenyl)azo)naphthalene-2-carboxamide
2-Naphthalenecarboxamide, 3-hydroxy-N-(2-methylphenyl)-4-((2,4,5-trichlorophenyl)azo)-
EINECS 229-440-3
UNII-6S30UYY7FD
Chemical Function
Dye
Pigment
Regulatory Lists
Europe; Personal care
banned; Europe; Personal care
Europe; plastic_additive
Europe; Toys and children's products
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Pigment Red 112 allowed in the EU?
Pigment Red 112 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Pigment Red 112 do in cosmetics?
Pigment Red 112 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 6535-46-2.
Is Pigment Red 112 used outside cosmetics?
Pigment Red 112 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Pigment Red 112 have different safety status in cosmetics vs industrial chemicals?
Pigment Red 112 is prohibited in EU cosmetics but has active industrial GHS classifications (H317, H411, H413).
Compliance Tools
Check Pigment Red 112 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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