Piper Marginatum Leaf Extract

INCI: PIPER MARGINATUM LEAF EXTRACT

CAS Number
Not established in CosIng databases
Function
Skin conditioning agent with ethnobotanical history of use for skin eruptions and rashes
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA listing; no CIR assessment available

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains aristolactams and aristolochic acid derivatives known as nephrotoxins and carcinogens; aristolochic acid absence must be confirmed via HPLC before cosmetic use; no HRIPT data available

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Piper Marginatum Leaf Extract safe in cosmetics?

Contains aristolactams and aristolochic acid derivatives known as nephrotoxins and carcinogens; aristolochic acid absence must be confirmed via HPLC before cosmetic use; no HRIPT data available The EU classifies Piper Marginatum Leaf Extract as "permitted". Safety rating: POOR.

Is Piper Marginatum Leaf Extract allowed in the EU?

Piper Marginatum Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Piper Marginatum Leaf Extract do in cosmetics?

Piper Marginatum Leaf Extract functions as: Skin conditioning agent with ethnobotanical history of use for skin eruptions and rashes. It is classified as a cosmetic ingredient in our database. CAS number: Not established in CosIng databases.

What is the Margin of Safety for Piper Marginatum Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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