Regulatory Status
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Safety Data
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Expert Verdict
Glutarimide pharmacophore present in teratogenic drugs (thalidomide, pomalidomide); while simple glutarimide is not classified as teratogenic, the structural alert demands robust safety justification in any CPSR; no SCCS opinion; no CIR review.
Frequently Asked Questions
Is Piperidinedione safe in cosmetics?
Glutarimide pharmacophore present in teratogenic drugs (thalidomide, pomalidomide); while simple glutarimide is not classified as teratogenic, the structural alert demands robust safety justification in any CPSR; no SCCS opinion; no CIR review. The EU classifies Piperidinedione as "permitted". Safety rating: POOR.
Is Piperidinedione allowed in the EU?
Piperidinedione EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Piperidinedione do in cosmetics?
Piperidinedione functions as: Skin conditioning (CosIng listed). It is classified as a cosmetic ingredient in our database. CAS number: 1121-89-7.
What is the Margin of Safety for Piperidinedione?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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