Regulatory Status
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Safety Data
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Expert Verdict
Polyglutamic acid is a fermentation-derived polyamino acid humectant with emerging clinical evidence supporting enhanced moisture retention compared to hyaluronic acid, though the evidence base remains less established. Fermentation-derived from Bacillus subtilis with good tolerability and no documented sensitization in cosmetic use. No regulatory restrictions in EU or US.
Regulatory Flags
Frequently Asked Questions
Is Polyglutamic Acid safe in cosmetics?
Polyglutamic acid is a fermentation-derived polyamino acid humectant with emerging clinical evidence supporting enhanced moisture retention compared to hyaluronic acid, though the evidence base remains less established. Fermentation-derived from Bacillus subtilis with good tolerability and no documented sensitization in cosmetic use. No regulatory restrictions in EU or US. The EU classifies Polyglutamic Acid as "permitted". Safety rating: EXCELLENT.
Is Polyglutamic Acid allowed in the EU?
Polyglutamic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Polyglutamic Acid do in cosmetics?
Polyglutamic Acid functions as: Humectant, skin-conditioning agent. Polyglutamic acid derived from Bacillus subtilis fermentation. Claims approximately 5× greater moisture retention than hyaluronic acid.. It is classified as a Humectant in our database. CAS number: 28829-38-1.
What is the Margin of Safety for Polyglutamic Acid?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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