Pregnenolone Acetate

INCI: PREGNENOLONE ACETATE

CAS Number
1778-02-5
Function
Skin conditioning agent with anti-aging and hydration properties
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically prohibited but hormonal claims would classify product as a drug. Cosmetic use at low concentrations exists historically.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Prohibited in EU cosmetics due to suspected carcinogenicity (H351), suspected reproductive toxicity (H361), and potential harm to breastfed children (H362). Classified as potential endocrine disruptor. Withdrawn from French market in 1992.

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Concern Level: High

Frequently Asked Questions

Is Pregnenolone Acetate safe in cosmetics?

Prohibited in EU cosmetics due to suspected carcinogenicity (H351), suspected reproductive toxicity (H361), and potential harm to breastfed children (H362). Classified as potential endocrine disruptor. Withdrawn from French market in 1992. The EU classifies Pregnenolone Acetate as "prohibited". Safety rating: POOR.

Is Pregnenolone Acetate allowed in the EU?

Pregnenolone Acetate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Pregnenolone Acetate do in cosmetics?

Pregnenolone Acetate functions as: Skin conditioning agent with anti-aging and hydration properties. It is classified as a cosmetic ingredient in our database. CAS number: 1778-02-5.

What is the Margin of Safety for Pregnenolone Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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