Rauwolfia Vomitoria Root Extract

Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes No explicit FDA cosmetic ban, but reserpine is a prescription drug substance with regulatory risk

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical โ€” Contains reserpine (EU Annex II prohibited), yohimbine (stimulant), and other bioactive alkaloids. No clinical safety studies for topical cosmetic use reported. Avoid unless alkaloid-depleted fraction is verified and documented.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Rauwolfia Vomitoria Root Extract safe in cosmetics?

Critical โ€” Contains reserpine (EU Annex II prohibited), yohimbine (stimulant), and other bioactive alkaloids. No clinical safety studies for topical cosmetic use reported. Avoid unless alkaloid-depleted fraction is verified and documented. The EU classifies Rauwolfia Vomitoria Root Extract as "prohibited". Safety rating: POOR.

Is Rauwolfia Vomitoria Root Extract allowed in the EU?

Rauwolfia Vomitoria Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What is the Margin of Safety for Rauwolfia Vomitoria Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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