Moderate Cosmetic Ingredient

Royal Jelly

INCI: ROYAL JELLY

CAS Number
8031-67-2
Function
skin conditioning agents
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
EU Max Conc. 20%
🇺🇸 US Status permitted
US Notes Permitted cosmetic ingredient under FD&C Act. Not FDA GRAS-classified. Not food GRAS-affirmed. CIR Expert Panel 2025: safe in cosmetics at present concentrations provided ingredient is free of pesticide residues and heavy metal contaminants (Pb ≤10 ppm, As ≤3 ppm, Hg ≤1 ppm).

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted in EU and US for cosmetic use. CIR 2025 assessed as safe under present practices with typical use 0.5-5% in leave-on products. Primary hazard is Type I and Type IV sensitization including documented fatal anaphylaxis; allergen labeling strongly advised for atopic and bee-allergic consumers. No margin of safety calculated due to lack of validated repeat-dose dermal study data.

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Concern Level: High

Regulatory Flags

skin-conditioning allergen-risk bee-derived natural-origin no-concentration-limit anaphylaxis-risk cross-reactive-allergen no-mos-calculated

Frequently Asked Questions

Is Royal Jelly safe in cosmetics?

Permitted in EU and US for cosmetic use. CIR 2025 assessed as safe under present practices with typical use 0.5-5% in leave-on products. Primary hazard is Type I and Type IV sensitization including documented fatal anaphylaxis; allergen labeling strongly advised for atopic and bee-allergic consumers. No margin of safety calculated due to lack of validated repeat-dose dermal study data. The EU classifies Royal Jelly as "permitted". Safety rating: MODERATE.

Is Royal Jelly allowed in the EU?

Royal Jelly EU regulatory status: permitted. Maximum allowed concentration: 20%. This is based on EU Regulation 1223/2009 and its amendments.

What does Royal Jelly do in cosmetics?

Royal Jelly functions as: skin conditioning agents. It is classified as a Cosmetic Ingredient in our database. CAS number: 8031-67-2.

What is the Margin of Safety for Royal Jelly?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Royal Jelly compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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