Regulatory Status
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Safety Data
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Expert Verdict
CRITICAL: Senecio genus is one of the primary sources of pyrrolizidine alkaloids, which are hepatotoxic, genotoxic, and potentially carcinogenic. Even dermal absorption of PAs poses systemic risk. SCCS and IFRA flag PA-containing botanicals. Must be analytically tested for PA content (< 1 ppb total PAs recommended). High regulatory scrutiny. Consider avoiding entirely unless PA-free status is analytically verified. [^1_20][^1_21]
Regulatory Flags
Frequently Asked Questions
Is Senecio Cannabifolius Extract safe in cosmetics?
CRITICAL: Senecio genus is one of the primary sources of pyrrolizidine alkaloids, which are hepatotoxic, genotoxic, and potentially carcinogenic. Even dermal absorption of PAs poses systemic risk. SCCS and IFRA flag PA-containing botanicals. Must be analytically tested for PA content (< 1 ppb total PAs recommended). High regulatory scrutiny. Consider avoiding entirely unless PA-free status is analytically verified. [^1_20][^1_21] The EU classifies Senecio Cannabifolius Extract as "permitted". Safety rating: POOR.
Is Senecio Cannabifolius Extract allowed in the EU?
Senecio Cannabifolius Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Senecio Cannabifolius Extract do in cosmetics?
Senecio Cannabifolius Extract functions as: Humectant [^1_20]. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng.
What is the Margin of Safety for Senecio Cannabifolius Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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