Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Squalane (Olive-derived). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | ca.10000 mg/kg bw/day | oral | rat | oral | REACH |
Dermal Penetration Profile
Skin absorption and penetration characteristics of Squalane (Olive-derived), relevant to systemic exposure and MoS calculations.
Source: Cosmetic Science
Expert Verdict
Olive-derived squalane is the preferred source over shark liver for sustainability and purity; ensure complete hydrogenation and verify peroxide value in certificate of analysis.
Regulatory Flags
Frequently Asked Questions
Is Squalane (Olive-derived) safe in cosmetics?
Olive-derived squalane is the preferred source over shark liver for sustainability and purity; ensure complete hydrogenation and verify peroxide value in certificate of analysis. The EU classifies Squalane (Olive-derived) as "permitted". Safety rating: EXCELLENT. 1 toxicological study endpoint(s) are available in our database.
Is Squalane (Olive-derived) allowed in the EU?
Squalane (Olive-derived) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Squalane (Olive-derived) do in cosmetics?
Squalane (Olive-derived) functions as: Emollient, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 111-01-3.
What is the Margin of Safety for Squalane (Olive-derived)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Squalane (Olive-derived)?
The NOAEL (No Observed Adverse Effect Level) for Squalane (Olive-derived) is ca.10000 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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