Moderate Surfactant NOAEL Data

Stearalkonium Chloride

INCI: STEARALKONIUM CHLORIDE

CAS Number
122-19-0
Function
Conditioning agent; antistatic; cationic surfactant
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 1โ€“3%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR assessed quaternary ammonium cationic surfactants as safe as used in rinse-off cosmetics. Cost-effective cationic conditioning agent. Incompatible with anionic surfactants. Used at 1โ€“3% in conditioners and cream rinses.

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Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Stearalkonium Chloride. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 50 mg/kg bw/day oral dog oral REACH
NOAEL 50 mg/kg bw/day oral dog oral REACH

Expert Verdict

Cost-effective C18 cationic surfactant used for conditioning and antistatic effects in rinse-off hair care. CIR confirmed safe as used. Moderate irritation potential as a cationic class ingredient, mitigated by rinse-off use at 1โ€“3%. Now frequently replaced by behentrimonium chloride or methosulfate variants in premium formulations, but remains common in standard and economy hair care. Incompatible with anionic surfactants.

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Concern Level: Moderate

Regulatory Flags

cationic quat conditioning anionic-incompatible rinse-off economy-grade

Frequently Asked Questions

Is Stearalkonium Chloride safe in cosmetics?

Cost-effective C18 cationic surfactant used for conditioning and antistatic effects in rinse-off hair care. CIR confirmed safe as used. Moderate irritation potential as a cationic class ingredient, mitigated by rinse-off use at 1โ€“3%. Now frequently replaced by behentrimonium chloride or methosulfate variants in premium formulations, but remains common in standard and economy hair care. Incompatible with anionic surfactants. The EU classifies Stearalkonium Chloride as "permitted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is Stearalkonium Chloride allowed in the EU?

Stearalkonium Chloride EU regulatory status: permitted. Maximum allowed concentration: 1โ€“3%. This is based on EU Regulation 1223/2009 and its amendments.

What does Stearalkonium Chloride do in cosmetics?

Stearalkonium Chloride functions as: Conditioning agent; antistatic; cationic surfactant. It is classified as a Surfactant in our database. CAS number: 122-19-0.

What is the Margin of Safety for Stearalkonium Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Stearalkonium Chloride?

The NOAEL (No Observed Adverse Effect Level) for Stearalkonium Chloride is 50 mg/kg bw/day based on a oral study via oral route in dog. A total of 2 study endpoints are available. Source: REACH.

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