Good Active Ingredient

Tamanu Oil

INCI: CALOPHYLLUM INOPHYLLUM SEED OIL

CAS Number
91770-46-6
Function
Emollient, wound-healing active, anti-inflammatory agent. Contains calophyllic acid, lactone with natural antibiotic properties, and calophyllolide with non-steroidal anti-inflammatory activity. Cold-pressed form preferred for maximum bioactive retention.
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Covered under CIR 2018 omnibus assessment of 244 plant-derived fatty acid oils; concluded safe as used. Not on FDA prohibited or restricted list. Two published case reports of contact dermatitis warrant patch test advisory.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Permitted in EU (not listed in restrictive Annexes II-VI of EC 1223/2009). US CIR 2018 group assessment of 244 plant-derived fatty acid oils concluded safe as used. Low systemic toxicity risk with negligible dermal absorption. Documented sensitization in two case reports warrants patch testing for sensitive individuals.

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Concern Level: Low

Regulatory Flags

contact-sensitization-risk limited-toxicology-data nut-tree-derived clusiaceae-cross-reactivity no-standalone-cir-assessment

Frequently Asked Questions

Is Tamanu Oil safe in cosmetics?

Permitted in EU (not listed in restrictive Annexes II-VI of EC 1223/2009). US CIR 2018 group assessment of 244 plant-derived fatty acid oils concluded safe as used. Low systemic toxicity risk with negligible dermal absorption. Documented sensitization in two case reports warrants patch testing for sensitive individuals. The EU classifies Tamanu Oil as "permitted". Safety rating: GOOD.

Is Tamanu Oil allowed in the EU?

Tamanu Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tamanu Oil do in cosmetics?

Tamanu Oil functions as: Emollient, wound-healing active, anti-inflammatory agent. Contains calophyllic acid, lactone with natural antibiotic properties, and calophyllolide with non-steroidal anti-inflammatory activity. Cold-pressed form preferred for maximum bioactive retention.. It is classified as a Active Ingredient in our database. CAS number: 91770-46-6.

What is the Margin of Safety for Tamanu Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Tamanu Oil compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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