Veratrum Oxysepalum Root Extract

INCI: VERATRUM OXYSEPALUM ROOT EXTRACT

CAS Number
Not specifically assigned (botanical extract)
Function
Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; no specific restrictions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: Same concerns as \#8 but amplified โ€” roots are the primary alkaloid accumulation site in *Veratrum* species. Veratridine and cevadine concentrations are highest in roots/rhizomes. Cyclopamine (teratogen) risk. This ingredient demands a full SCCS-level safety dossier, specified alkaloid limits, validated analytical methods, and batch-to-batch consistency data. Would strongly recommend avoiding this ingredient unless a compelling efficacy case exists with robust safety data to support it

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Veratrum Oxysepalum Root Extract safe in cosmetics?

CRITICAL: Same concerns as \#8 but amplified โ€” roots are the primary alkaloid accumulation site in *Veratrum* species. Veratridine and cevadine concentrations are highest in roots/rhizomes. Cyclopamine (teratogen) risk. This ingredient demands a full SCCS-level safety dossier, specified alkaloid limits, validated analytical methods, and batch-to-batch consistency data. Would strongly recommend avoiding this ingredient unless a compelling efficacy case exists with robust safety data to support it The EU classifies Veratrum Oxysepalum Root Extract as "permitted". Safety rating: POOR.

Is Veratrum Oxysepalum Root Extract allowed in the EU?

Veratrum Oxysepalum Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Veratrum Oxysepalum Root Extract do in cosmetics?

Veratrum Oxysepalum Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned (botanical extract).

What is the Margin of Safety for Veratrum Oxysepalum Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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