Moderate Cosmetic Ingredient NOAEL Data

ZIRCONYL DIOXIDE

CAS Number
1314-23-4
Function
Opacifying
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Restricted
EU Max Conc. II/391
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

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Toxicological Studies

2 study endpoints found for ZIRCONYL DIOXIDE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 3156 mg/kg bw/day oral rat oral REACH
NOAEL 3156 mg/kg bw/day oral rat oral REACH

Expert Verdict

ZIRCONYL DIOXIDE is listed in the EU CosIng database with functions: Opacifying It is restricted under EU Cosmetics Regulation. Restriction: II/391.

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Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted needs-enrichment

Frequently Asked Questions

Is ZIRCONYL DIOXIDE safe in cosmetics?

ZIRCONYL DIOXIDE is listed in the EU CosIng database with functions: Opacifying It is restricted under EU Cosmetics Regulation. Restriction: II/391. The EU classifies ZIRCONYL DIOXIDE as "Restricted". Safety rating: MODERATE. 2 toxicological study endpoint(s) are available in our database.

Is ZIRCONYL DIOXIDE allowed in the EU?

ZIRCONYL DIOXIDE EU regulatory status: Restricted. Maximum allowed concentration: II/391. This is based on EU Regulation 1223/2009 and its amendments.

What does ZIRCONYL DIOXIDE do in cosmetics?

ZIRCONYL DIOXIDE functions as: Opacifying. It is classified as a cosmetic ingredient in our database. CAS number: 1314-23-4.

What is the NOAEL for ZIRCONYL DIOXIDE?

The NOAEL (No Observed Adverse Effect Level) for ZIRCONYL DIOXIDE is 3156 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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