2,4-Diaminophenol HCl

INCI: 2,4-DIAMINOPHENOL HCL

CAS Number
137-09-7 (formerly listed as dihydrochloride; CIR updated nomenclature to HCl)
Function
Oxidative hair dye coupler
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR: Safe for use in hair dyes at โ‰ค0.2% (expressed as free base)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU Annex II ban; genotoxicity data; restricted even under US CIR to very low concentrations

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Concern Level: High

Frequently Asked Questions

Is 2,4-Diaminophenol HCl safe in cosmetics?

EU Annex II ban; genotoxicity data; restricted even under US CIR to very low concentrations The EU classifies 2,4-Diaminophenol HCl as "prohibited". Safety rating: POOR.

Is 2,4-Diaminophenol HCl allowed in the EU?

2,4-Diaminophenol HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,4-Diaminophenol HCl do in cosmetics?

2,4-Diaminophenol HCl functions as: Oxidative hair dye coupler. It is classified as a cosmetic ingredient in our database. CAS number: 137-09-7 (formerly listed as dihydrochloride; CIR updated nomenclature to HCl).

What is the Margin of Safety for 2,4-Diaminophenol HCl?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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