Regulatory Status
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Safety Data
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Expert Verdict
2,5-Hexanedione is a neurotoxic metabolite responsible for peripheral neuropathy and cross-links neurofilament proteins causing progressive nerve damage. Classified as Repr. 2 (H361f) under CLP; use in cosmetics should be avoided.
Regulatory Flags
Frequently Asked Questions
Is Acetonylacetone (2,5-Hexanedione) safe in cosmetics?
2,5-Hexanedione is a neurotoxic metabolite responsible for peripheral neuropathy and cross-links neurofilament proteins causing progressive nerve damage. Classified as Repr. 2 (H361f) under CLP; use in cosmetics should be avoided. The EU classifies Acetonylacetone (2,5-Hexanedione) as "prohibited". Safety rating: POOR.
Is Acetonylacetone (2,5-Hexanedione) allowed in the EU?
Acetonylacetone (2,5-Hexanedione) EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetonylacetone (2,5-Hexanedione) do in cosmetics?
Acetonylacetone (2,5-Hexanedione) functions as: Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 110-13-4.
What is the Margin of Safety for Acetonylacetone (2,5-Hexanedione)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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