Acetyl Tetrapeptide-15

CAS 928007-64-1. Not listed in EU Annex II (prohibited) or Annex III (restricted). Registered in CosIng with no concentration limit. No SCCS opinion issued. No CIR safety assessment published. ECHA C&L: 104 of 104 notifications report no GHS hazard classification. Mechanistically sound neurotransmitter-inhibiting peptide (mu-opioid receptor agonism, CGRP suppression) with clinical evidence at 0.0015% active. Primary regulatory limitation is absence of independent public toxicology data — safety substantiation relies on supplier dossier (Lubrizol/Lipotec). Suitable for use in cosmetics at recommended supplier levels (0.2-6% of trade solution), but EU Article 10 Safety Assessments requiring full toxicological dossiers will need direct access to the supplier's confidential data package or commissioned independent testing. The EU classifies Acetyl Tetrapeptide-15 as "permitted". Safety rating: GOOD.

Acetyl Tetrapeptide-15 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

Acetyl Tetrapeptide-15 functions as: Skin conditioning, neurotransmitter-inhibiting (mu-opioid receptor agonist, CGRP release inhibition for sensitive skin). It is classified as a cosmetic ingredient in our database. CAS number: 928007-64-1.

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.