Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3)
INCI: PALMITOYL PENTAPEPTIDE-4
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Well-characterized anti-aging peptide (Matrixyl) approved by CIR (2024). Non-sensitizing, non-mutagenic, non-phototoxic with no endocrine activity. Used at very low concentrations (0.001-0.012% leave-on) with clean global regulatory profile.
Frequently Asked Questions
Is Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) safe in cosmetics?
Well-characterized anti-aging peptide (Matrixyl) approved by CIR (2024). Non-sensitizing, non-mutagenic, non-phototoxic with no endocrine activity. Used at very low concentrations (0.001-0.012% leave-on) with clean global regulatory profile. The EU classifies Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) as "permitted". Safety rating: GOOD.
Is Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) allowed in the EU?
Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) do in cosmetics?
Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3) functions as: Skin conditioning agent, Collagen stimulator. It is classified as a cosmetic ingredient in our database. CAS number: 214047-00-4.
What is the Margin of Safety for Palmitoyl Pentapeptide-4 (formerly Palmitoyl Pentapeptide-3)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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