Adenium Obesum Leaf Extract

INCI: ADENIUM OBESUM LEAF EXTRACT

CAS Number
Not assigned
Function
Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical concern: Adenium obesum leaf extract contains toxic cardiac glycosides including oleandrin analogs; direct leaf extracts retain these compounds and require mandatory analytical screening and robust safety assessment under Article 10 of EC 1223/2009 before cosmetic use.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Adenium Obesum Leaf Extract safe in cosmetics?

Critical concern: Adenium obesum leaf extract contains toxic cardiac glycosides including oleandrin analogs; direct leaf extracts retain these compounds and require mandatory analytical screening and robust safety assessment under Article 10 of EC 1223/2009 before cosmetic use. The EU classifies Adenium Obesum Leaf Extract as "permitted". Safety rating: POOR.

Is Adenium Obesum Leaf Extract allowed in the EU?

Adenium Obesum Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Adenium Obesum Leaf Extract do in cosmetics?

Adenium Obesum Leaf Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Adenium Obesum Leaf Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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