Good Fragrance Sensitization Data

Anthemis Nobilis Flower Oil

INCI: ANTHEMIS NOBILIS FLOWER OIL

CAS Number
8015-92-7
Function
Fragrance, skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. No concentration limit; constituent allergens (linalool, limonene, geraniol) require label declaration above 0.001% (leave-on) / 0.01% (rinse-off) per Annex III
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS under 21 CFR 182.10 (spices/natural seasonings) and 182.20 (essential oils); no FDA cosmetic restriction; no GRASE classification

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Anthemis Nobilis Flower Oil based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; literature review

Expert Verdict

Roman chamomile oil with CIR safe as used conclusion (2013), GRAS status, and negative phototoxicity/genotoxicity profile. Sensitization risk low in general population; Compositae-sensitive individuals may cross-react due to constituent allergens. Formulation should minimize aggregate sensitizer load when combining multiple botanicals, and GC-MS CoA should be obtained for constituent allergen labeling compliance.

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Concern Level: Low

Regulatory Flags

fragrance allergen-declaration-required compositae-cross-reactivity eu_children_restricted ifra_fragrance fda_food_additive

Frequently Asked Questions

Is Anthemis Nobilis Flower Oil safe in cosmetics?

Roman chamomile oil with CIR safe as used conclusion (2013), GRAS status, and negative phototoxicity/genotoxicity profile. Sensitization risk low in general population; Compositae-sensitive individuals may cross-react due to constituent allergens. Formulation should minimize aggregate sensitizer load when combining multiple botanicals, and GC-MS CoA should be obtained for constituent allergen labeling compliance. The EU classifies Anthemis Nobilis Flower Oil as "permitted". Safety rating: GOOD.

Is Anthemis Nobilis Flower Oil allowed in the EU?

Anthemis Nobilis Flower Oil EU regulatory status: permitted. Maximum allowed concentration: No concentration limit; constituent allergens (linalool, limonene, geraniol) require label declaration above 0.001% (leave-on) / 0.01% (rinse-off) per Annex III. This is based on EU Regulation 1223/2009 and its amendments.

What does Anthemis Nobilis Flower Oil do in cosmetics?

Anthemis Nobilis Flower Oil functions as: Fragrance, skin conditioning. It is classified as a Fragrance in our database. CAS number: 8015-92-7.

What is the Margin of Safety for Anthemis Nobilis Flower Oil?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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