Poor Cosmetic Ingredient NOAEL Data GHS Classified

Benzotriazole

INCI: BENZOTRIAZOLE

CAS Number
95-14-7
Function
Antimicrobial
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status restricted
🇺🇸 US Status permitted
US Notes Not specifically prohibited; not listed as a color additive. No FDA monograph. Permitted by default under FD&C Act unless proven unsafe.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Benzotriazole. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL ca.6700 ppm oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is irritating to the eyes.
Long-term Exposure Effects
Repeated or prolonged contact may cause skin sensitization.
Routes of Exposure
The substance can be absorbed into the body by inhalation of its aerosol and by ingestion.

Expert Verdict

Proposed CMR classification (Carcinogenic 2, Reproductive 2); environmental endocrine disruptor with environmental persistence concerns; SCCS review likely pending.

⚠️
Concern Level: High

Frequently Asked Questions

Is Benzotriazole safe in cosmetics?

Proposed CMR classification (Carcinogenic 2, Reproductive 2); environmental endocrine disruptor with environmental persistence concerns; SCCS review likely pending. The EU classifies Benzotriazole as "restricted". Safety rating: POOR. 1 toxicological study endpoint(s) are available in our database.

Is Benzotriazole allowed in the EU?

Benzotriazole EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Benzotriazole do in cosmetics?

Benzotriazole functions as: Antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 95-14-7.

What is the Margin of Safety for Benzotriazole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Benzotriazole?

The NOAEL (No Observed Adverse Effect Level) for Benzotriazole is ca.6700 ppm based on a oral study via oral route in rat. Source: REACH.

Compliance Tools

Check Benzotriazole compliance across multiple jurisdictions:

🔬
Ingredient Decoder
Paste a full ingredient list for instant analysis
 🌸
82 Allergen Checker
Check for EU declarable fragrance allergens
 🧪
Substance Compliance
Check compliance across 55 jurisdictions
 🧮
MoS Calculator
Calculate Margin of Safety using SCCS methodology
 ⚗️
Heavy Metal Limits
Compare limits across jurisdictions

Related Ingredients

Pentasodium Aminotrimethylene Phosphonate
Moderate
Ethyl Estradiolcarboxylate
Poor
Aluminum Chloride
Moderate
Ammonium Thiolactate
Moderate
Dimethyl Glutamic Acid
Moderate
Browse all 30,000+ ingredients →
📱

Is Benzotriazole in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Benzotriazole in your formulation.

Ingredient Decoder MoS Calculator