Good Active Ingredient SCCS/CIR Reviewed Dermal Penetration

Calendula Extract (Calendula Officinalis Flower Extract)

INCI: CALENDULA EXTRACT

CAS Number
84776-23-8
Function
Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir 7 January 2001
Verdict: unknown

Dermal Penetration Profile

Skin absorption and penetration characteristics of Calendula Extract (Calendula Officinalis Flower Extract), relevant to systemic exposure and MoS calculations.

Absorption %
2-5%
Penetration Level
surface
Penetration Depth
stratum corneum
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
minimal
Topical Bioavailability
1-3%
Safety Margin Factor
low
Vehicle Dependent
Yes โ€” absorption varies by formulation

Source: Phytother Res

Expert Verdict

Good safety profile. Generally considered safe for cosmetic use.

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Concern Level: Low

Regulatory Flags

eu_children_restricted

Frequently Asked Questions

Is Calendula Extract (Calendula Officinalis Flower Extract) safe in cosmetics?

Good safety profile. Generally considered safe for cosmetic use. The EU classifies Calendula Extract (Calendula Officinalis Flower Extract) as "permitted". Safety rating: GOOD. This ingredient has been reviewed by cir.

Is Calendula Extract (Calendula Officinalis Flower Extract) allowed in the EU?

Calendula Extract (Calendula Officinalis Flower Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Calendula Extract (Calendula Officinalis Flower Extract) do in cosmetics?

Calendula Extract (Calendula Officinalis Flower Extract) functions as: Antioxidant. It is classified as a Active Ingredient in our database. CAS number: 84776-23-8.

What is the Margin of Safety for Calendula Extract (Calendula Officinalis Flower Extract)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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