Chamomilla Recutita Flower Extract

INCI: CHAMOMILLA RECUTITA FLOWER EXTRACT

CAS Number
84082-60-0
Function
Hydroethanolic or glycolic extract of Matricaria chamomilla (German chamomile) flowers. Principal actives: (-)-alpha-bisabolol (anti-inflammatory, wound healing, penetration enhancer) and chamazulene (anti-inflammatory, characteristic blue colour formed during steam distillation from matricine). Inhibits arachidonic acid-derived inflammatory mediators via 5-LOX and COX-1/2 suppression. Additional flavonoid content (apigenin, luteolin) contributes antioxidant and soothing activity. Widely used in sensitive-skin, atopic, and wound-healing formulations.
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. โ‰ค0.5% leave-on
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted without restriction. Sesquiterpene lactone content (Compositae/Asteraceae family) relevant for cross-sensitization in confirmed composite-sensitive individuals. MoCRA safety substantiation required.

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Chamomilla recutita flower extract is a well-established anti-inflammatory and soothing botanical active used across sensitive-skin, atopic, wound-healing, and baby-care formulations. Core actives are (-)-alpha-bisabolol and chamazulene. Anti-inflammatory mechanism involves 5-LOX and COX-1/2 pathway inhibition. The extract belongs to the Asteraceae (Compositae) family: sesquiterpene lactone cross-sensitization is documented in Compositae-allergic individuals, though German chamomile's lactone profile is lower-risk than arnica or Roman chamomile. EU and US permitted without restriction. Standardisation to bisabolol content via HPLC is recommended for batch-to-batch consistency.

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Concern Level: Low

Regulatory Flags

asteraceae-family sensitizer-compositae-crossreaction anti-inflammatory soothing wound-healing bisabolol-source chamazulene-source eu_children_restricted

Frequently Asked Questions

Is Chamomilla Recutita Flower Extract safe in cosmetics?

Chamomilla recutita flower extract is a well-established anti-inflammatory and soothing botanical active used across sensitive-skin, atopic, wound-healing, and baby-care formulations. Core actives are (-)-alpha-bisabolol and chamazulene. Anti-inflammatory mechanism involves 5-LOX and COX-1/2 pathway inhibition. The extract belongs to the Asteraceae (Compositae) family: sesquiterpene lactone cross-sensitization is documented in Compositae-allergic individuals, though German chamomile's lactone profile is lower-risk than arnica or Roman chamomile. EU and US permitted without restriction. Standardisation to bisabolol content via HPLC is recommended for batch-to-batch consistency. The EU classifies Chamomilla Recutita Flower Extract as "permitted". Safety rating: GOOD.

Is Chamomilla Recutita Flower Extract allowed in the EU?

Chamomilla Recutita Flower Extract EU regulatory status: permitted. Maximum allowed concentration: โ‰ค0.5% leave-on. This is based on EU Regulation 1223/2009 and its amendments.

What does Chamomilla Recutita Flower Extract do in cosmetics?

Chamomilla Recutita Flower Extract functions as: Hydroethanolic or glycolic extract of Matricaria chamomilla (German chamomile) flowers. Principal actives: (-)-alpha-bisabolol (anti-inflammatory, wound healing, penetration enhancer) and chamazulene (anti-inflammatory, characteristic blue colour formed during steam distillation from matricine). Inhibits arachidonic acid-derived inflammatory mediators via 5-LOX and COX-1/2 suppression. Additional flavonoid content (apigenin, luteolin) contributes antioxidant and soothing activity. Widely used in sensitive-skin, atopic, and wound-healing formulations.. It is classified as a Active Ingredient in our database. CAS number: 84082-60-0.

What is the Margin of Safety for Chamomilla Recutita Flower Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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