Convallaria Majalis Bulb/Root Extract
INCI: CONVALLARIA MAJALIS BULB/ROOT EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
CRITICAL: Contains convallatoxin and other cardiac glycosides with anticancer (cytotoxic) activity. Inhibits cell proliferation, induces apoptosis, suppresses angiogenesis in breast and colorectal cancer cells — demonstrating significant biological potency. Bulb/root is the most toxic plant part. Banned in China for cosmetics. Use in cosmetics is extremely high-risk and would require comprehensive dermal absorption, repeat-dose dermal toxicity, and cardiac safety studies.
Regulatory Flags
Frequently Asked Questions
Is Convallaria Majalis Bulb/Root Extract safe in cosmetics?
CRITICAL: Contains convallatoxin and other cardiac glycosides with anticancer (cytotoxic) activity. Inhibits cell proliferation, induces apoptosis, suppresses angiogenesis in breast and colorectal cancer cells — demonstrating significant biological potency. Bulb/root is the most toxic plant part. Banned in China for cosmetics. Use in cosmetics is extremely high-risk and would require comprehensive dermal absorption, repeat-dose dermal toxicity, and cardiac safety studies. The EU classifies Convallaria Majalis Bulb/Root Extract as "prohibited". Safety rating: POOR.
Is Convallaria Majalis Bulb/Root Extract allowed in the EU?
Convallaria Majalis Bulb/Root Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Convallaria Majalis Bulb/Root Extract do in cosmetics?
Convallaria Majalis Bulb/Root Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84082-46-2.
What is the Margin of Safety for Convallaria Majalis Bulb/Root Extract?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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