Croton Gratissimus Seed Extract

INCI: CROTON GRATISSIMUS SEED EXTRACT

CAS Number
Not assigned / not publicly listed
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restriction; not CIR-reviewed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical data gap: No published safety assessment. Croton genus plants contain diterpenoid esters (phorbol esters) which are potent skin irritants and tumor promoters. Requires full toxicological dossier before CPSR approval.

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Concern Level: High

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Croton Gratissimus Seed Extract safe in cosmetics?

Critical data gap: No published safety assessment. Croton genus plants contain diterpenoid esters (phorbol esters) which are potent skin irritants and tumor promoters. Requires full toxicological dossier before CPSR approval. The EU classifies Croton Gratissimus Seed Extract as "prohibited". Safety rating: POOR.

Is Croton Gratissimus Seed Extract allowed in the EU?

Croton Gratissimus Seed Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Croton Gratissimus Seed Extract do in cosmetics?

Croton Gratissimus Seed Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly listed.

What is the Margin of Safety for Croton Gratissimus Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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