Di-C12-13 Alkyl Malate

INCI: DI-C12-13 ALKYL MALATE

CAS Number
Not assigned (mixture of diesters)
Function
Skin-conditioning agent — emollient
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not prohibited or restricted under 21 CFR; CIR reviewed and concluded safe

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Acute oral LD50 >5000 mg/kg (very low toxicity); not mutagenic in Ames test or micronucleus assay; not a dermal or ocular irritant at 100%; 28-day repeat-dose dermal study in rabbits showed no adverse effects.

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Concern Level: Low

Frequently Asked Questions

Is Di-C12-13 Alkyl Malate safe in cosmetics?

Acute oral LD50 >5000 mg/kg (very low toxicity); not mutagenic in Ames test or micronucleus assay; not a dermal or ocular irritant at 100%; 28-day repeat-dose dermal study in rabbits showed no adverse effects. The EU classifies Di-C12-13 Alkyl Malate as "permitted". Safety rating: EXCELLENT.

Is Di-C12-13 Alkyl Malate allowed in the EU?

Di-C12-13 Alkyl Malate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Di-C12-13 Alkyl Malate do in cosmetics?

Di-C12-13 Alkyl Malate functions as: Skin-conditioning agent — emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (mixture of diesters).

What is the Margin of Safety for Di-C12-13 Alkyl Malate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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